The following paper provides research analysis on the influence of wind on a building, considering the regional and local climate conditions, to improve dynamic stability and reduce wind disruption effects on high-rise reinforced concrete buildings. The main aspect of disturbance in living conditions is caused by wind loads on the building. The data is based on structural analysis, generated by the “Lira CAD 2013” software, for a construction project of a 19-story residential building, completed in Georgia’s capital Tbilisi, 58 Kavtaradze St., in accordance with the given necessary requirements and restrictions by general terms and conditions of the Georgian state law. Computer aided modeling provides the ability to simulate and define parameters caused by the wind disruption on an actual site. Calculation process is based on variables specified by state law for each region of the country. Modified accelerations which have been caused by wind in multi-story, high-rise buildings have significantly greater values on upper floors, and reaching the edges of the minimum living comfort criteria. The given study features the estimation for high-rise buildings under various combinations of loads. High-rise buildings have gone under significant restrictions due to use of conventional rigid frames as structural elements in the construction process. That process tends to develop a series of new research and findings for proper architectural forms, which became possible using the new generation of fast digital computing software and hardware.